We are developing chemical tools to address fundamental problems in biology and human health. Click on the links below to learn more about our research program and take a look at our publications. If you are interested in applying some of our methodologies in your research, feel free to request any materials.
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We are working to design novel systems for covalent modification of biomolecules, including the design of peptide- and DNA-based molecules for site-specific protein modification.
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Molecules designed to generate an immune response for diagnostic and therapeutic applications are a major research topic in the lab. Our main approach is via re-engineered T cells.
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We are genetically re-wiring cellular circuitry in order to give proteins and organisms new functions. Our main approach is the expansion of the genetic code with unnatural amino acids.
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Light enables the regulation of biological processes with high spatial and temporal resolution, and we are engineering light-responsive nucleic acids and proteins for optobiological studies.
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